Cish isoforms

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August undefined, 2024

WebCISH INFORMATION. Proteini. Full gene name according to HGNC. Cytokine inducible SH2 containing protein. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. CISH (CIS, CIS-1, G18, SOCS) Protein classi. … WebKey features and details Rabbit polyclonal to CISH/CIS - C-terminal Suitable for: IHC-P, WB Reacts with: Rat, Human Isotype: IgG You may also be interested in Protein Recombinant Human CISH/CIS protein (ab117057) Primary Anti-C6orf134/TAT antibody (ab184778) Secondary Goat Anti-Rabbit IgG H&L (HRP) (ab205718) View more associated products …

Anti-CISH antibody produced in mouse - Sigma-Aldrich

WebCIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in … WebThe protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS) also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI) protein family. ionioner water boiler

Gene - CISH

WebJan 27, 2006 · Chromogenic in-situ hybridization (CISH) is a relatively new method for detection of gene amplification using a peroxidase reaction, which can be viewed using a standard light microscope. This ... WebAnti-CISH antibody produced in mouse. IgG fraction of antiserum, buffered aqueous solution. View Price and Availability. ... Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Immunogen. CISH (NP_659508.1, 1 a.a. ~ 258 a.a) full-length human protein. Sequence. Packaging. 100 μg. WebCIS contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine … on tech customer reviews in nashville tn

Frontiers SOCS Proteins in Immunity, Inflammatory Diseases, and ...

Chromogenic in-situ hybridization: a viable alternative to

WebRecombinant Human CISH/CIS protein is a Wheat germ Full length protein 1 to 258 aa range and validated in WB, ELISA, SDS-PAGE. ... and to a lesser extent in lung. The tissue distribution of isoforms 1 and 1B is distinct. Pathway. Protein modification; protein ubiquitination. Sequence similarities. Contains 1 SH2 domain. Contains 1 SOCS box … WebCISH depends upon the ability of labeled DNA and RNA probes to hybridize (bind) in situ to specific sequences of complementary DNA or RNA in the tissue sample. CISH with DNA probes is sometimes referred to as DISH, while CISH with RNA probes is called RISH. Probe hybridization results are then imaged within the context of the surrounding tissue ... on tech arizonaWebSOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that … ion ion bond example

"WebNov 1, 2014 · The founding member of the SOCS family, cytokine inducible SH2-containing protein (CISH), and the seven other members present in mammals, SOCS-1 to -7, share a common structure. All SOCS proteins contain a central SH2 domain with an N-terminal extended SH2 subdomain (ESS) and a C-terminal 40 amino acid (aa) motif, the SOCS box. " - Cish isoforms

Cish isoforms

Tissue expression of CISH - Summary - The Human …

WebThe MiTF antibody recognizes serine phosphorylated and non-phosphorylated melanocytic isoforms of microphthalmia. It is useful in identifying Malignant Melanoma, and distinguishing mast cell lesions from lesions of myeloid derivation. A relatively rare class of tumors known as PEComas (tumors showing perivascular epithelioid cell differentiation) … WebMar 21, 2024 · CISH (Cytokine Inducible SH2 Containing Protein) is a Protein Coding gene. Diseases associated with CISH include Bacteremia 2 and Malaria . Among its related pathways are IL3-mediated signaling …

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WebMultiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] Chromosome. 3: Cytoband. p21.2: Chromosome location (bp) 50606490 - 50611831: Protein evidence: Evidence at protein level : ... CISH-001: ENSP00000294173 ENST00000348721: WebThe expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. For Research Use Only.

WebMar 28, 2024 · Cish, participates within a multi-molecular E3 ubiquitin ligase complex, which ubiquitinates target proteins. It has an inhibitory effect on T cell activation mediated by PLC-γ1 regulation, and ... WebSOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 …

WebJan 14, 2024 · CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF … WebThe protein encoded by CISH has a predicted amino acid length of 258 and a mass of 28.7 kDa. There are currently 3 reported isoforms. CISH may also be known by the following …

WebOct 5, 2024 · One of the potential targets for cytokine-mediated activation of NK cells is the CIS protein. CIS is a SH 2 -containing cytokine-induced protein encoded by the CISH gene. CIS decreases the susceptibility of NK cells to IL-15 and thus is a powerful check point for inactivation of their cytotoxicity.

WebIsotype: IgG You may also be interested in Protein Recombinant Human CISH/CIS protein (ab117057) Primary Anti-USP51 antibody (ab121147) Secondary Goat Anti-Rabbit IgG … on te charrieWebAug 1, 2024 · Manipulation of intrinsic factors that inhibit T cell effector function and neoantigen recognition may therefore improve TIL therapy outcomes. We previously identified the cytokine-induced SH2... ontech denver coWebIsoforms are assumed to have similar functional properties, as most have similar sequences, and share some to most exons with the canonical sequence. However, some … ontech door lockWebHome / Human / CISH Antibody. Western blot analysis of extracts of 293T cells, using CISH antibody (15-585) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. … ion ion ionWebWe believe a successful engagement starts by CISTECH listening to your requirements. Then together we define a vision to create value and a plan to achieve it. Whatever the … ion ion interaction exampleWebFluorescence in situ hybridization (FISH) technologies enable rapid detection of chromosome aberrations in all manner of tissues, including both fresh and archival specimens. These technologies have gained broad acceptance in the clinical cytogenetic and research communities. ion-ion forces examplesWebMultiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. ... There are no reviews for CISH/CIS-1 Lysate (NBL1-09216). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount. Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen ... ontech careers